Osteochondral allograft

Written by Dr Sheila Strover on March 14, 2025

An osteochondral allograft is transplant of a plug of bone and cartilage from a donor into a prepared matching defect in the patient.

A plug of cartilage and bone is harvested from the donor bone block, and press-fitted into the prepared recipient area.

Illustration of the front of the knee to show the bone block in place.

Viability of allograft plugs

This technique is usually reserved for large cartilage defects, where the cartilage damage is full thickness.

Fresh allograft is purchased from a tissue bank as a block of bone and cartilage, from which the surgeon harvests the plug. The success of the procedure depends upon the viability of the fresh cells, which can only be stored for a month or two after any necessary processing.

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